2-Phenoxyethanol is a glycol ether used as a preservative in vaccines. Get CDCs official recommended immunization schedules for children, adolescents, and adults. Side effects are more common in younger people. Zostavax is made from the whole but . People with a history of severe allergic reaction (e.g., anaphylaxis) to any component of the vaccine or after a previous dose of Shingrix. Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. Formaldehyde is used in vaccines to inactivate the virus so the person being inoculated does not contract the disease. People with minor illnesses, such as a cold, may be vaccinated. VZV can reactivate many years later, causing shingles. Shingrix is also recommended for adults 19 years and older who have weakened immune systems because of disease or therapy. Thank you for taking the time to confirm your preferences. Vaccine recipients may take over-the-counter pain medicine like ibuprofen or acetaminophen to ease discomfort from these side effects. We can make that appointment now. Before you administer Shingrix, CDC recommends counseling your patients about the common reactions to the vaccine. 33. Common Ingredients: tris hydrochloride, tris base, glutamate (monosodium salt), proline, salt, monopotassium phosphate, potassium chloride, magnesium chloride, calcium chloride, ferrous sulfate, ascorbic acid, niacin, glutathione. Two doses of Shingrix provides more than 90% protection against shingles and postherpetic neuralgia (PHN), the most common complication of shingles. Listed below are vaccine ingredients (substances that appear in the final vaccine product), process ingredients (substances used to create the vaccine that may or may not appear in the final vaccine product), and growth mediums (the substances vaccines are grown in) for vaccines licensed for use by the Food & Drug Administration (FDA). In addition to the rash, shingles can cause fever, headache, chills, or upset stomach. 2021), Madin Darby Canine Kidney (MDCK) cells, culture medium, -propiolactone, cetyltrimethylammonium bromide, phosphate buffered saline, MDCK cell protein, protein other than HA, MDCK cell DNA, polysorbate 80, cetyltrimethylammonium bromide, propiolactone, thimerosal, Influenza Virus Vaccine (Trivalent, Types A and B), Afluria Southern Hemisphere Package Insert (2021), Afluria: allantoic fluid of embryonated chicken eggs, sucrose density gradient, beta375 propiolactone, sodium taurodeoxycholate, phosphate buffered isotonic solution, Afluria Southern Hemisphere: allantoic fluid of embryonated chicken eggs, sucrose density gradient, beta-propiolactone, sodium taurodeoxycholate, phosphate buffered isotonic solution, Afluria: sodium chloride, monobasic sodium, phosphate, dibasic sodium phosphate, monobasic potassium phosphate, potassium chloride, calcium chloride, sodium taurodeoxycholate, ovalbumin, sucrose, neomycin sulfate, polymyxin B, beta-propiolactone, hydrocortisone, Afluria Southern Hemisphere: thimerosal, sodium chloride, monobasic sodium phosphate, dibasic sodium phosphate, monobasic potassium phosphate, potassium chloride, calcium chloride, sodium taurodeoxycholate, ovalbumin, sucrose, neomycin sulfate, polymyxin B, beta-propiolactone, hydrocortisone, phosphate-buffered saline solution, thimerosal, ovalbumin, formaldehyde, sodium deoxycholate, -tocopheryl hydrogen succinate, polysorbate 80, Influenza Vaccine, Live, Intranasal (Trivalent, Types A and B), [Editors Note: This vaccine was approved on July 9, 2020, and, as of Nov. 1, 2021, the FDA had not uploaded the package insert. Remind your patients that the pain from shingles can last a lifetime, and these side effects should only last 2 to 3 days. Prices have fluctuated slightly in 2019, with Shingrix at $185 per injection ( two injections required, between two and six months apart) and Zostavax at $296 for the single dose needed. Common side effects, such as soreness and redness at the injection site, are usually mild to moderate in intensity and resolve quickly on their own. Adverse reactions should be reported to the Vaccine Adverse Event Reporting System (VAERS). Your health care provider will usually file this report, or you can do it yourself. Three vaccines licensed for use by the FDA (plague, poliovax, and rabies vaccine adsorbed) are listed on the FDA site, but do not have available package inserts or other information, and thus are not included below. Vaccines for preventing herpes zoster in older adults, Update on Recommendation for Use of Herpes Zoster Vaccine. 68.2% among adult autologous hematopoietic cell transplant recipients. Safety and tolerability of zoster vaccine in adults 60 years old. Safety of Zostavax-A cohort study in a managed care organization. Saving Lives, Protecting People, National Center for Immunization and Respiratory Diseases, U.S. Department of Health & Human Services. Cochrane Database Syst Rev. The two-dose vaccine is more than 90% effective at preventing shingles, the CDC reports. Answer: The Canadian Immunization Guide provides a list of ingredients for all approved vaccines in Canada. Cookies used to enable you to share pages and content that you find interesting on CDC.gov through third party social networking and other websites. It can live undetected in our bodies for years after causing chickenpox until it erupts into a. People sometimes faint after medical procedures, including vaccination. Alternatives. 2011 Nov;7(11):1130-6. While Shingrix is not contraindicated in immunocompromised people, the Advisory Committee on Immunization Practices (ACIP) at this time does not recommend it for this population. Additionally, though the Moderna and Janssen (Johnson & Johnson) COVID-19 (coronavirus) vaccines were approved by the FDA for emergency use, they have not yet received full FDA approval for non-emergency use as of Nov. 17, 2021, and thus are not included below. Healy, S. Teleki, A.V. CDC twenty four seven. 2021), sodium chloride, monobasic sodium phosphate, dibasic sodium phosphate, and polysorbate 20 (Tween20), baculovirus and Spodoptera frugiperda cell proteins, baculovirus and cellular DNA, Triton X-100, Influenza Vaccine,Live, Intranasal (Quadrivalent, Types A and Types B), FluMist Quadrivalent Package Insert (Aug. 2021), specific pathogen-free (SPF) eggs, stabilizing buffer, monosodium glutamate, hydrolyzed porcine gelatin, arginine, sucrose, dibasic potassium phosphate, monobasic potassium phosphate, ovalbumin, gentamicin sulfate, ethylenediaminetetraacetic acid (EDTA), Influenza Virus Vaccine (Quadrivalent, Types A and Types B), Manufacturer: Glaxosmithkline Biologicals, Fluarix Quadrivalent Package Insert (2021), octoxynol-10 (TRITON X-100), tocopheryl hydrogen succinate, polysorbate 80 (Tween 80), hydrocortisone, gentamicin sulfate, ovalbumin, formaldehyde, sodium deoxycholate, Fluzone High-Dose Quadrivalent Package Insert (July 2021), Fluzone Quadrivalent Package Insert (2021), Fluzone Intradermal Quadrivalent Package Insert (May 10, 2016), Fluzone Quadrivalent Southern Hemisphere Package Insert (2021), Fluzone High-Dose Quadrivalent: embryonated chicken eggs, formaldehyde, linear sucrose density gradient solution, octylphenol ethoxylate (Triton X-100), sodium phosphate-buffered isotonic sodium chloride solution, Fluzone Quadrivalent: embryonated chicken eggs, formaldehyde, linear sucrose density gradient solution , octylphenol ethoxylate (Triton X-100), sodium phosphate-buffered isotonic sodium chloride solution, Fluzone Intradermal Quadrivalent: embryonated chicken eggs, formaldehyde, linear sucrose density gradient solution, octylphenol ethoxylate (Triton 17 X-100), sodium phosphate-buffered isotonic sodium chloride solution, Fluzone Quadrivalent Southern Hemisphere: embryonated chicken eggs, formaldehyde, linear sucrose density gradient solution, octylphenol ethoxylate (Triton X-100), sodium phosphate-buffered isotonic sodium chloride solution, Fluzone High-Dose Quadrivalent: sodium phosphate-buffered isotonic sodium chloride solution, formaldehyde, octylphenol ethoxylate, gelatin, Fluzone Quadrivalent: thimerosal, sodium phosphate-buffered isotonic sodium chloride solution, formaldehyde, octylphenol ethoxylate, Fluzone Intradermal Quadrivalent: sodium phosphate-buffered isotonic sodium chloride solution, formaldehyde, octylphenol ethoxylate, Fluzone Quadrivalent Southern Hemisphere: thimerosal, sodium phosphate-buffered isotonic sodium chloride solution, formaldehyde, octylphenol ethoxylate, Flulaval Quadrivalent Package Insert (2021), phosphate-buffered saline solution, ovalbumin, formaldehyde, sodium deoxycholate, -tocopheryl hydrogen succinate, polysorbate 80, Japanese Encephalitis Virus Vaccine, Inactivated, Adsorbed, Vero cells, protamine sulfate, sucrose density gradient, formaldehyde, aluminum hydroxide, formaldehyde, bovine serum albumin, host cell DNA, sodium metabisulphite, host cell protein, protamine sulfate, 23. In addition to the rash, shingles can cause fever, headache, chills, or upset stomach. Also called Tween 80, Alkest 80, or Canarcel 80 (brand names), Polysorbate 80 is used as an excipient (something to basically thicken a vaccine for proper dosing) and an emulsifier (something to bond the ingredients). These cookies perform functions like remembering presentation options or choices and, in some cases, delivery of web content that based on self-identified area of interests. Recommendations of the Advisory Committee on Immunization Practices for Use of Herpes Zoster Vaccines, 2018. A New Vaccine to Prevent Herpes Zoster, NEJM. Tseng HF, Liu A, Sy L, Marcy SM, Fireman B, et al. Centers for Disease Control and Prevention. Thank you for taking the time to confirm your preferences. Shingles can cause severe pain that can last for months. Shingles vaccination is the only way to protect against shingles and postherpetic neuralgia (PHN), the most common complication from shingles. DTap-HepB-IPV Vaccine(diphtheria, tetanus, pertussis, hepatitis B, & polio), Diphtheria & Tetanus Toxoids & Acellular Pertussis Vaccine Adsorbed, Hepatitis B (recombinant) and Inactivated Poliovirus Vaccine Combined, Fenton medium containing a bovine extract, Latham medium derived from bovine casein, formaldehyde, Stainer-Scholte liquid medium, glutaraldehyde, genetically engineered Saccharomyces cerevisiae (S. cerevisiae) cells, VERO cells, calf serum, lactalbumin hydrolysate, aluminum hydroxide, aluminum phosphate, filamentous hemagglutinin (FHA), pertactin (69 kiloDalton outer membrane protein), HBsAg, aluminum salts, sodium chloride, formaldehyde, polysorbate 80 (Tween 80), neomycin sulfate, polymyxin B, yeast protein, 10. CDC recommends the shingles vaccine (Shingrix) for adults 50 and older, Give Shingrix to immunocompetent adults 50 years and older, including those who. Prevention of herpes zoster: Recommendations of the Advisory Committee on Immunization Practices (ACIP). In 8 clinical trials of more than 10,000 participants: CDC and FDA monitor the safety of vaccinesafter they are approved or authorized. They help us to know which pages are the most and least popular and see how visitors move around the site. 2012 May;271(5):510-20. Vaccination is a safe and effective way to protect you from serious disease caused by shingles. Safety of Zoster Vaccine in Elderly Adults Following Documented Herpes Zoster. Ask your health care provider for guidance. All information these cookies collect is aggregated and therefore anonymous. Tell your provider if you feel dizzy or have vision changes or ringing in the ears. They help us to know which pages are the most and least popular and see how visitors move around the site. It does not have a live virus. Murray AV, Reisinger KS, Kerzner B, Stek JE, Sausser TA, et al. After you have chickenpox, the virus stays in your body and can cause shingles later in life. You will be subject to the destination website's privacy policy when you follow the link. Getting vaccinated is the best way to prevent shingles. This vaccine is safe and may be used until the supply expires (before or by November 2020). Common Ingredients: Cells from normal female adult Cocker Spaniel (harvested in 1958 by SH Madin and NB Darby), EMEM(EBSS) (Eagle's Minimum Essential Medium with Earle's Balanced Salt Solution), glutamine, non essential amino acids, foetal bovine serum. Centers for Disease Control and Prevention. pain, redness, or swelling where the shot was given. MRC-5 cells [DNA, protein], sodium phosphate monobasic, EDTA, neomycin, fetal bovine serum, Refrigerator: sucrose, phosphate, glutamate, processed gelatin, urea, sucrose, hydrolyzed gelatin, sodium chloride, monosodium L-glutamate, sodium phosphate dibasic, potassium phosphate monobasic, potassium chloride, MRC-5 cells [DNA, protein], neomycin, bovine calf serum, living avian leukosis virus-free (ALV-free) chicken embryos, sorbitol, gelatin, sterile diluent [sodium chloride injection], Zostavax Frozen Package Insert (Jan. 2019), Zostavax Refrigerator Stable Package Insert (Aug. 2018), Frozen: sucrose, hydrolyzed porcine gelatin, sodium chloride, monosodium L-glutamate, sodium phosphate dibasic, potassium phosphate monobasic, potassium chloride, MRC-5 cells [DNA, protein], neomycin, bovine calf serumsucrose, hydrolyzed porcine gelatin, sodium chloride, monosodium L-glutamate, sodium phosphate dibasic, potassium phosphate monobasic, potassium chloride, MRC-5 cells [DNA, protein], neomycin, bovine calf serum, Refrigerator Stable: sucrose, hydrolyzed porcine gelatin, urea, sodium chloride, monosodium L-glutamate, sodium phosphate dibasic, potassium phosphate monobasic, potassium chloride, MRC-5 cells [DNA, protein], neomycin, bovine calf serum, genetically engineered Chinese hamster ovary cells, growth media [amino acids], AS01B [3-O-desacyl-4-monophosphoryl lipid A (MPL) from Salmonella minnesota, QS-21 (saponin purified from plant extract Quillaja saponaria Molina), liposomal formulation (dioleoyl phosphatidylcholine (DOPC), cholesterol, phosphate-buffered saline solution (disodium phosphate anhydrous, potassium dihydrogen phosphate, sodium chloride, water for injection))], sucrose, sodium chloride, DOPC, potassium dihydrogen phosphate, cholesterol, sodium dihydrogen phosphate dihydrate, disodium phosphate anhydrous, dipotassium phosphate, polysorbate 80, host cell proteins, host cell DNA, Acumedia Manufacturers, Mueller Hinton Agar (7101), neogen.com, June 2011, Atlanta Biologicals, Earles Balanced Salt Solution (EBSS), atlantabio.com, 2010, CDC, Basics and Common Questions: Ingredients of Vaccines Fact Sheet, cdc.gov, Feb. 22, 2011, FDA, Vaccines Licensed for Immunization and Distribution in the US with Supporting Documents, fda.gov, Aug. 29, 2016, Health Protection Agency, General Cell Collection: MDCK, hpacultures.org.uk, 2011, G.M. Efficacy, safety, and tolerability of herpes zoster vaccine in persons aged 50-59 years. All information these cookies collect is aggregated and therefore anonymous. The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. Chicago, Illinois 60654 USA, Natalie Leppard Ether used as a cold, may be used until the supply (... Adults 60 years old U.S. Department of health & Human Services official recommended Immunization schedules for children,,. Patients that the pain from shingles can cause shingles later in life they are or... You administer shingrix, CDC recommends counseling your patients that the pain from shingles and... Av, Reisinger KS, Kerzner B, et al for disease Control and prevention ( CDC ) not! Best way to Prevent shingles in a managed care organization or have vision or. That you find interesting on CDC.gov through third party social networking and other websites can severe. 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